Baylor Reports 27 Births From 44 Uterus Transplants, With High Complication Rates

Baylor University Medical Center in Dallas has recorded 27 births from uterus transplantation as of April 2026, according to the largest case series published to date. U.S. birth in 2017.

She and her colleagues published their findings in the Journal of the American Medical Association on May 1. From 2016 to 2026, 44 women had uterus transplantation at Baylor, which has the largest uterus transplant center in the world. A month after surgery, 37 of the 44 women had a successfully transplanted uterus.

As of April 2026, 33 of those with successful transplants had embryos transferred. Thirty-one of the 33 women became pregnant, and 27 have given birth. Eight of the 27 women who gave birth experienced complications, most commonly gestational diabetes or high blood pressure.

Of the 27 women, 23 had one child and four had two children each. All newborns had an Apgar score of at least 7 out of 10 at five minutes. Eleven of the newborns were admitted to the neonatal intensive care unit due to prematurity.

Their stays ranged from a few days to almost two months. Science News reported that no malformations tied to the transplant itself occurred. Around one in 500 women do not have a functioning womb, a condition known as absolute uterine factor infertility.

It occurs when a woman is born without a uterus, has had it removed or has a defective organ. More than 70 babies have been born globally following uterus transplantation in the last decade, with uteruses coming from both living and deceased donors. Baylor has used almost exclusively living donors.