Brazilian Researchers Test Jackfruit-Based Gel on Stem Cells for Gum Disease Treatment

Researchers at the Pontifical Catholic University of São Paulo developed a biomaterial that combines jackfruit latex, pomegranate peel extract, and simvastatin to treat severe gum disease. The research was published today in the journal Polymer Bulletin. The material was tested using human stem cells derived from fat tissue.

2 per cent. None of the three concentrations compromised the gel's structural integrity, and all were deemed safe for potential use. Every concentration triggered osteoinduction within a fortnight, with effects intensifying by day 21.

Professor Eliana Aparecida de Rezende Duek coordinated the study. "We began to view latex extracted from jackfruit as an interesting alternative, as it has adhesive properties," Professor Duek stated. " "Overall, the results were very encouraging for us," she said.

Periodontitis is a chronic inflammatory condition triggered by bacterial infection that progressively destroys the supporting structures around teeth. Pomegranate peel extract was incorporated for its germ-fighting properties when applied directly to tissue.

Simvastatin has demonstrated anti-inflammatory effects and the ability to encourage bone formation in previous studies.