Crinetics Pharmaceuticals to Present Six Abstracts at ENDO 2026
Crinetics Pharmaceuticals will present six abstracts at the Endocrine Society's Annual Meeting in Chicago from June 13-16, 2026. The presentations cover clinical data on PALSONIFY for acromegaly and atumelnant for congenital adrenal hyperplasia and Cushing's syndrome.
bleedingcool.comCrinetics Pharmaceuticals announced that data from six abstracts will be presented at the Endocrine Society's Annual Meeting, ENDO 2026, scheduled for June 13-16, 2026, in Chicago. Three abstracts will report data on PALSONIFY (paltusotine) in acromegaly.
An oral presentation will feature long-term efficacy and pooled safety data from the PATHFNDR-1 and PATHFNDR-2 open-label extension studies covering up to two years of treatment.
Two poster presentations will address additional aspects of PALSONIFY use. One evaluates real-world biochemical control in acromegaly using U.S. claims and laboratory data. The second assesses long-term safety and efficacy of PALSONIFY in combination with cabergoline from the ACROBAT Advance trial.
Three abstracts will cover the atumelnant clinical development program. Oral presentations will include full Phase 2 data in congenital adrenal hyperplasia and interim results from a Phase 1b/2a study in ACTH-dependent Cushing's syndrome. A rapid-fire presentation will highlight dose selection data for the Phase 3 trial in congenital adrenal hyperplasia.
A company endocrinologist stated that the presentations will increase the depth of clinical evidence supporting the long-term safety and efficacy of PALSONIFY for acromegaly treatment and will characterize the potential of atumelnant for treating diseases of ACTH excess.
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