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Researchers in France, Spain and Germany have diagnosed clusters of dermatophilosis, a bacterial skin infection typically seen in livestock, among men who have sex with men with no known animal contact. All reported cases have been mild, presenting as rashes or pustules in areas exposed during sexual contact, and have resolved with antibiotics or without treatment.
Substrate placeholder — needs reviewEuropean researchers have identified clusters of dermatophilosis infections among men who have sex with men in Spain, France and Germany. The skin condition, caused by the bacterium Dermatophilus congolensis, typically affects livestock and had previously been reported in humans only in cases involving direct animal contact.
None of the diagnosed men reported exposure to livestock. The first clusters were documented in Barcelona and Lyon. Vicente Descalzo, an internal medicine specialist in the STI/HIV unit at Barcelona’s Drassanes-Hospital Vall d’Hebron, was the first author of the Spanish paper.
Matthieu Degreze, a junior scientist at the University Hospital of Lyon, led the French study. Both teams reported that most infected men had attended saunas before developing symptoms. The primary symptom is a rash with pimples or pustules appearing in areas of the body exposed during sexual contact.
All cases to date have been mild and have either cleared without intervention or responded to antibiotics. Genetic sequencing of bacterial samples from eight cases in Lyon showed close similarity. The Lyon researchers wrote that the genomic relatedness and shared sexual exposures suggest interhuman transmission within sexual networks.
The Barcelona team reported similar genetic findings among its nine initial cases, indicating a single introduction of the bacterium into that community. After the papers were posted online, a physician in Berlin contacted Descalzo to report additional cases in Germany.
Since submitting its paper, the Lyon team has identified 25 cases total across Lyon, Paris, Bordeaux, Saint-Etienne and Annecy. Two of those individuals had recent travel to Turkey and Italy. The bacterium is known to spread more efficiently in humid environments.
Didier Pin, a veterinarian at VetAgro Sup in Lyon, stated in an email that humidity is a very important factor in the development of Dermatophilus congolensis. Descalzo cautioned that the role of saunas remains a hypothesis. Demetre Daskalakis, chief medical officer at the Callen-Lorde Community Health Center in New York City and a former director of the CDC’s division of HIV prevention, said the condition appears to present as benign folliculitis.
He noted uncertainty about how the infection might affect people with compromised immune systems, including those with uncontrolled HIV. None of the cases in the reported clusters involved immunocompromised individuals. Both Descalzo and Degreze believe the condition is underdiagnosed because of its mild symptoms.
Daskalakis agreed that increased awareness among health care providers and researchers will likely lead to identification of additional cases. The World Health Organization said it is aware of the reports and emphasized the importance of testing for unusual skin lesions in sexual health services.
Human infections with dermatophilosis have previously been documented only rarely, including in a girl who attended a horseback riding camp and in tourists who rode elephants in Thailand. In animals the condition is known by names such as rain scald or rain rot and is usually mild but can occasionally become more severe.
Researchers have not determined whether individuals without visible lesions can transmit the bacterium. The Barcelona group has confirmed one additional case beyond its initial nine, while Descalzo reported hearing from other local physicians who have seen similar cases.
The Lyon and Barcelona teams had not compared their bacterial sequences with each other at the time of publication. Daskalakis suggested that sauna operators and attendees should emphasize hygiene practices. He added that advising people to avoid such venues is unlikely to be effective.
Descalzo said that for physicians experienced in sexually transmitted infections, the presentation does not appear to overlap significantly with mpox symptoms.
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