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Several pharmaceutical companies began selling lower-cost versions of semaglutide weight-loss drugs in India following the key patent's expiration in March. Mounjaro has become one of the top-selling drugs in a country with the world's second-highest number of overweight adults and more than 77 million people with Type 2 diabetes.
pandaily.comSeveral Indian pharmaceutical companies began selling cheaper generic brands of semaglutide after the key patent on the drug expired in India in March. The development has intensified competition in the weight-loss market and driven down prices across the sector. Ozempic and Wegovy now sell for as little as $20 in India for a low dose, according to Novo Nordisk India.
Generic brands are priced up to 70 per cent less than that. Mounjaro has become one of the top selling drugs in India. The country has the world's second-highest number of overweight adults and more than 77 million people with Type 2 diabetes, according to The Lancet medical journal.
18 billion) before the end of this decade, according to Pharmarack. To sell a generic version of an approved drug in India, companies must demonstrate bioequivalence and bioavailability to the Central Drugs Standard Control Organisation.
While the patent for Mounjaro has not yet expired in India, the increased competition with generic semaglutide drugs hitting the market has seen prices slashed across the sector. Pankhuri Pareek consulted a doctor after her BMI exceeded 30 following pregnancy weight gain. She was prescribed Mounjaro containing tirzepatide.
"I consulted a doctor, told her that my BMI is getting over 30 and this is not what I want for myself because I want to be fit for myself and my daughter," Ms Pareek told the ABC. Ms Pareek took IV drips to maintain nutrients and hydration while using Mounjaro. She increased strength training to prevent muscle loss while using Mounjaro.
"Everything started getting normal; I feel better as a human being, I feel fitter," she said. Jennifer Joseph was advised by her doctor to lose at least 20 kilograms after an unrelated health scare. She began taking Mounjaro in January at a weight of 104 kilograms and lost six kilograms in the first month.
"It was no longer optional; Mounjaro was not an impulsive decision, it was medically advised, researched and taken consciously," she told the ABC. Doctor Preethi Mrinalini is a laparoscopic and bariatric surgeon in Chennai who takes Mounjaro. She said she did not recommend the new generic brands of weight loss drugs because there was not enough adequate research or trial data.
Doctor Preethi Mrinalini receives daily enquiries about weight loss drugs including from people who are not overweight. "One good thing that's actually happened is obesity awareness," Doctor Preethi Mrinalini said. She turns away many people who want a prescription but are not considered obese.
"I know for a fact they are able to get themselves on it somehow, which is not OK," she said. Amita Gadre is a nutritionist in Pune. She said the drugs are now available through multiple channels raising the risk of obtaining them without proper medical supervision.
"What I'd like to see as a healthcare professional is mandatory registration of patients on these medications with a monitoring system, clear digital prescription trails, so pharmacies cannot dispense without verification, and standardised patient counselling requirements before any prescription is issued," Ms Gadre said.
India supplies about 20 per cent of the world's generic medicines, according to the Global Trade Research Initiative. Patents on semaglutide drugs are due to expire in 10 countries this year.
The Therapeutic Goods Administration said new generic weight loss drugs from India would not be allowed to sell in Australia. Patents for Wegovy and Ozempic in Australia do not expire until October 2038. Abc reported that a competing product cannot be approved simply because a patent expires and that manufacturers must still meet Australia's regulatory requirements.
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