science
Study Identifies New Alzheimer's Risk Genes Tied to Immunity
A proteome-wide association study found several new candidate risk genes for Alzheimer's disease linked to innate and adaptive immunity. The analysis examined cohorts of European American and African American ancestry.
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A proteome-wide association study identified several new putative risk genes for Alzheimer's disease that are involved in innate and adaptive immunity. The study drew on cohorts of people of European American and African American ancestry.
Researchers conducted the analysis using protein-level data across the participant groups. The approach allowed examination of genetic associations at the protein level rather than solely at the DNA-sequence level.
The newly identified genes participate in immune-system pathways. The results add to existing evidence connecting immune function with Alzheimer's disease risk.
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