science
Study Links Mitochondrial DNA Mutations to Health After Age 60
Research published in Nature reports increased mitochondrial DNA mutations after age 60. The mutations remain hidden until they form clones and may affect health separately from clonal hematopoiesis.
May 27, 11:24 AM·1m read1 source
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A study published in Nature examined mitochondrial DNA changes that occur with aging. The research found a marked accumulation of mutations after age 60. These mutations stay undetected until they expand into clones.
The study noted that while the mutations are associated with clonal hematopoiesis, also called CHIP, they may have independent effects on health outcomes. The findings add to existing knowledge about how mitochondrial DNA alterations accumulate over time. Researchers indicated the mutations could influence health even when not linked to CHIP.
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