YouTuber Daniel Coleman Says Son Isaac Died After Cancer Diagnosis

, wrote on social media Friday that his 14-year-old son Isaac died the previous day after a cancer diagnosis made five months earlier. Coleman stated that Isaac was born with Fanconi anemia, a rare genetic disorder that impairs DNA repair and raises the risk of bone marrow failure and cancer.

The boy had already undergone kidney and bone marrow transplants before age 11.

December, Coleman reported that Isaac received a cancer diagnosis in his mouth and underwent an eight-hour surgery to remove the tumor. A February update stated the cancer had reached stage 3, and Coleman canceled his 2026 live show tour to focus on his son’s care.

was born October 3, 2011, in Huntersville, North Carolina, weighing just over three pounds. He required early surgeries for a brain shunt and colostomy and was awaiting a bone marrow transplant by age three. Coleman launched the Danny Go! channel in 2019, producing music videos that have drawn more than four million subscribers.

He has used the platform to promote organ donation and bone marrow registry participation. Coleman and his wife Mindy also have a 10-year-old son named Levi.