Topic
immunotherapy
20 stories related to this topic, newest first.
The Guardianscience13 days ago
New Pancreatic Cancer Drug Doubles Survival Time in Trial
A daily pill extended median survival from 6.5 to 13.5 months for patients with advanced pancreatic cancer in a 500-person study. Separate early trials showed a smart drug shrank tumors in six common cancers, and observational data linked GLP-1 weight-loss drugs to lower cancer r…
thequint.comscience16 days ago
Large NCI-Funded Phase 3 Trial Tests Probiotic CBM588 With Immunotherapy in Advanced Kidney Cancer
A multicenter study funded by the National Cancer Institute will test whether CBM588 improves outcomes when taken with immunotherapy in nearly 700 people with advanced renal cell carcinoma.
foxnews.comscience28 days ago
Cancer Immunotherapy Pipeline Expands With Multiple New Drug Classes
More than 2,500 cancer immunotherapy programs are now active. Fifteen years after the first checkpoint inhibitor approval, several additional drug types have reached FDA approval or late-stage testing.
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prweb.comscience29 days ago
Study Examines How Anti-PD-1 Antibodies Affect Immune Cell Signaling
A new study published in Science Immunology reports that anti-PD-1 antibodies trap PD-1 proteins at nanoscale immune contacts and trigger inhibitory checkpoint signaling. The findings identify potential targets for improving immunotherapy design.
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ncbi.nlm.nih.govtechnology34 days ago
CAR-T Cell Therapy Shows Early Promise for Long-Term HIV Control
A small clinical trial tested CAR-T cell therapy in nine people with HIV. Two participants maintained undetectable virus levels for up to 20 months after stopping antiretroviral drugs.
medpagetoday.comscience38 days ago
NHS Approves Durvalumab for Treatment of Resectable Stomach Cancer
The National Institute for Health and Care Excellence has approved the immunotherapy drug durvalumab, also known as Imfinzi and made by AstraZeneca, for use by the NHS in adults with stomach cancer that has not spread extensively and can be surgically removed. An estimated 1,500…
The Independentworld40 days ago
Small Study Shows Modified Immune Cells Suppress HIV in Two Patients
Researchers reported that a single dose of genetically engineered CAR-T cells strongly suppressed HIV in two people for nearly one and two years without daily medication. The early-stage experiment modified immune cells to better target HIV-infected cells while protecting them fr…
thehindubusinessline.comscience41 days ago
Two Patients Achieve Undetectable HIV Levels After Experimental Engineered Immune Cell Treatment
Scientists report that a single infusion of modified immune cells enabled two people to suppress HIV to undetectable levels, one for nearly two years. The findings, presented as proof of concept, draw on a decade of success using similar techniques against blood cancers. Research…
medium.comai45 days ago
Machine-Learning Analysis Identifies Nine Conserved Spatial Ecotypes Across Human Tumors
Researchers integrated more than 10 million single-cell and spot-level spatial transcriptomes from diverse human carcinomas and melanomas to define nine spatial ecotypes. Each ecotype shows unique biology, geospatial features and clinical outcome associations, including links to…
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Substrate placeholder — needs reviewscience46 days ago
Peanut Allergy Treatment Succeeds in 82 Percent of Toddlers in Swedish Study
Researchers at Karolinska Institutet treated children aged one to three years with peanut allergies by feeding them gradually increasing small amounts of peanut puffs over three years. After the treatment period, 82 percent of children in the treatment group could eat at least th…
link.springer.comai46 days ago
Machine Learning Framework Identifies Tumor Microenvironment Ecotypes in Blood Samples
Researchers developed a machine learning approach that identifies nine spatial ecotypes in the tumor microenvironment from over 10 million single-cell and spatial transcriptomes across multiple cancer types. The ecotypes can be detected noninvasively through cell-free DNA methyla…
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The Timesscience48 days ago
NHS Rolls Out One-Minute Injection for Key Cancer Drug, Cutting Treatment Time
The UK's National Health Service is introducing an injectable form of the immunotherapy drug pembrolizumab, reducing administration time from up to two hours via intravenous drip to under a minute. This change affects treatment for 14 types of cancer and could benefit about 14,00…
Substrate placeholder — needs reviewworld72 days ago
Study Finds Relacorilant May Extend Survival in Platinum-Resistant Ovarian Cancer Patients
A clinical trial showed that adding relacorilant to standard treatment extended median survival by 4.1 months for patients with platinum-resistant ovarian cancer. The study involved 381 participants and reported a 35 percent reduction in mortality risk. Separately, another trial…
Substrate placeholder — needs reviewscience72 days ago
Challenges in Targeting Cancer Tumors with Immunotherapies and Viral Proteins
Immunotherapies and viral proteins that induce cell death serve as tools in cancer treatment. These methods face difficulties in selectively targeting tumors without affecting healthy cells. Researchers continue to explore ways to improve precision in such therapies.
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Substrate placeholder — needs reviewworld73 days ago
Researchers Report CAR-T Cell Therapy Success in Severe Autoimmune Disease Case
A 47-year-old woman with three severe autoimmune diseases received experimental CAR-T cell therapy in early 2025 after nine failed treatments. The therapy, originally developed for cancer, targets problematic immune cells to induce remission. The patient has since returned to nor…
Substrate placeholder — needs reviewscience73 days ago
Nature Publishes Three New Research Papers on Plant Immunity, Genetic Disease Risks, and Cancer Immunotherapy
Nature journal released three research papers on October 10, 2024, addressing advancements in rice disease resistance, genetic repeat expansions linked to brain atrophy, and synthetic enhancers for viral immunotherapy. The studies highlight genetic mechanisms for crop protection,…
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BruceBlaus / Wikimedia (CC BY-SA 4.0)science73 days ago
Nature Publishes Three Research Papers on Genetics, Immunotherapy, and Social Science Reproducibility
Nature has released three new research papers addressing distinct scientific areas. One study analyzes population-scale repeat expansions to link them with disease risk and brain atrophy. Another develops synthetic super-enhancers for targeted viral immunotherapy, while a third e…
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science74 days ago
Nature Publishes Four New Research Papers on Superconductivity, Immunotherapy, Reproducibility, and Brain Activity
Nature journal released four research papers covering advancements in materials science, medical treatments, scientific methodology, and neuroscience. The papers address superconductivity in nickelate thin films, synthetic super-enhancers for viral immunotherapy, reproducibility…
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Substrate placeholder — needs reviewscience74 days ago
Nature Publishes Four New Research Papers on Superconductivity, Immunotherapy, Reproducibility, and Brain Activity
Nature journal released four research papers covering advancements in materials science, medical treatments, scientific methodology, and neuroscience. The papers address superconductivity in nickelate thin films, synthetic super-enhancers for viral immunotherapy, reproducibility…
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Substrate placeholder — needs reviewscience74 days ago
Nature Publishes Four New Research Papers on Diverse Scientific Topics
Nature journal released four research papers covering advancements in viral immunotherapy, reproducibility in social sciences, neural activity dissociation, and chemical catalysis for olefins production. Each paper presents findings from specialized studies in biology, economics,…
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