Topic
pharmacology
4 stories related to this topic, newest first.
Fox Newsscience23 days ago
Review Finds Single Ketamine Infusion Reduced Depression Symptoms Within Hours
A review of 26 clinical trials found that one intravenous ketamine dose lowered depression scores in four hours and suicidal thoughts within 24 hours. Effects lasted up to a month for some participants. Researchers noted the drug is not FDA-approved for depression treatment.
rediff.comscience38 days ago
Experimental Quintuple Agonist Outperforms Semaglutide in Mouse Obesity Models
A quintuple agonist developed by researchers at Helmholtz Munich combines GLP-1, GIP and PPAR activity to target five receptor systems. The compound reduced body weight, fat mass and blood sugar more effectively than existing therapies in several mouse models. Scientists caution…
sciencealert.comscience44 days ago
Metformin Acts Primarily Through Gut Mitochondrial Complex I Inhibition
A study published in Nature Metabolism found that metformin, a widely prescribed drug for type 2 diabetes, lowers blood glucose mainly by inhibiting mitochondrial complex I in the intestinal epithelium rather than in the liver. The research used human metabolomic data and mouse g…
ER
Substrate placeholder — needs reviewworld73 days ago
Study Identifies Genetic Variations Influencing Response to Weight-Loss Drugs Wegovy and Mounjaro
Researchers analyzed genetic data from 15,000 individuals to identify variations linked to weight-loss outcomes and side effects from medications like Wegovy and Mounjaro. The study, published in Nature, found that certain variants affect weight reduction and nausea or vomiting s…