Substrate
Topic

proteomics

2 stories related to this topic, newest first.

Thousands of Previously Uncatalogued Micropeptides Given Formal Name 'Peptideins' and Added to Major Databaseslink.springer.com
science20 days agoDeveloping

Thousands of Previously Uncatalogued Micropeptides Given Formal Name 'Peptideins' and Added to Major Databases

An effort announced today in Nature gives thousands of previously overlooked molecules encoded by the human genome the official name peptideins. The reclassification includes them in major gene and protein databases used by the life-sciences community. Some peptideins have been i…

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Ribosome Profiling of 80 Human Hearts Identifies Hundreds of Small Proteins Encoded by Previously Non-Coding Regionsncbi.nlm.nih.gov
health23 days agoDeveloping

Ribosome Profiling of 80 Human Hearts Identifies Hundreds of Small Proteins Encoded by Previously Non-Coding Regions

In 2019 systems biologist Sebastiaan van Heesch used ribosome profiling on donated hearts, many from end-stage heart failure patients, and discovered hundreds of mini-proteins encoded by noncoding genome regions. Many of the dark proteins targeted mitochondria, potentially affect…

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