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senescent-cells

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Researchers Identify GPX4 Inhibitors That Target Senescent Cells in Cancer ModelsSubstrate placeholder — needs review
science35 days agoDeveloping

Researchers Identify GPX4 Inhibitors That Target Senescent Cells in Cancer Models

A study has identified GPX4 inhibitors that selectively kill senescent cells, which accumulate in tumors after chemotherapy. These compounds showed effectiveness in preclinical models of melanoma, prostate, and ovarian cancer. The findings suggest a potential new strategy for can…

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