Topic
stem-cell-biology
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yahoo.comscience31 days ago
Study Links DNMT3A Mutations to Accelerated Aging Features
Researchers examined Heyn–Sproul–Jackson syndrome caused by DNMT3A gain-of-function mutations. The mutations produced DNA hypermethylation that impaired adult stem cell function and produced age-related changes in blood, bone, and metabolic tissues in both humans and mice.
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