Mark Cuban and President Trump Announce Expansion of TrumpRx Drug Site

Mark Cuban stood beside President Trump at the White House on Monday to announce a major expansion of the TrumpRx site. The site will add more than 600 generic medications through Cuban’s Cost Plus Drugs company, alongside Amazon Pharmacy and GoodRx.

The announcement came after Cuban spent 2024 campaigning for the Democratic presidential nominee. ” Cuban had also described President Trump as “unethical” in a public exchange with Vivek Ramaswamy. When a reporter asked about the unusual pairing, President Trump told Cuban, “Well, he made a mistake.

” Cuban responded that he would not discuss his 2024 political activities. cost nearly three times more than in other developed countries. Pharmacy benefit managers, which manage roughly 80 percent of prescriptions filled in the U.S., receive rebates based on list prices and keep a portion rather than passing savings to patients.

Cuban’s Cost Plus Drugs model purchases generics directly from manufacturers and adds a 15 percent margin plus dispensing and shipping fees. One cancer drug listed at more than $2,000 at conventional pharmacies appears at roughly $17 on the Cost Plus site.

A February 2026 commentary by Jeffrey Sonnenfeld of the Yale School of Management stated that many brand-name drugs on the site were cheaper through traditional insurance or existing discount programs. The New York Times reported that some TrumpRx prices were twice as high as those in other wealthy nations.

At least 350 branded medications saw price increases at the start of 2026. The most expensive brand-name and specialty drugs remain largely outside the current expansion.