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Study Reveals Coffee Alters Gut Microbiome and Mood with Benefits from Both Caffeinated and Decaf
A new study published in Nature Communications shows regular coffee consumption influences the gut-brain axis, affecting microbiome composition, inflammation, and emotional traits. Researchers found distinct benefits from caffeinated and decaffeinated coffee on stress, depression, anxiety, and other health markers.
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A study published this week in Nature Communications explores how regular coffee consumption influences the gut-brain axis, revealing changes in microbiome composition, reduced inflammation, and effects on mood and behavior. Wired reported that scientists at APC Microbiome Ireland compared 31 healthy adults who regularly consume coffee with 31 non-coffee drinkers, detecting alterations in bacteria such as Eggerthella species and Cryptobacterium curtum among drinkers.
These bacteria contribute to gastric and intestinal acid secretion, bile acid synthesis, and the elimination of harmful intestinal bacteria to prevent infections.
John Cryan, a coauthor of the study and principal investigator at APC Microbiome Ireland, a research center at the University of Cork, stated in a press release, 'Coffee is more than just caffeine; it’s a complex dietary factor that interacts with our gut microbes, our metabolism, and even our emotional well-being.
The study analyzed effects when coffee consumers suspended intake for two weeks, noting decreases in impulsiveness and emotional reactivity, along with initial symptoms like fatigue or headache. Regular coffee drinkers showed higher levels of impulsiveness and emotional reactivity compared to non-coffee drinkers.
Researchers then examined resumption of intake for two weeks with either caffeinated or decaffeinated coffee. Both types reduced perceived stress and certain indicators of depression. Caffeinated coffee was associated with improvements in anxiety and some aspects of attention, while decaffeinated coffee showed benefits in memory, sleep quality, and physical activity.
