Substrate
Topic

T cells

5 stories related to this topic, newest first.

Small Study Shows Modified Immune Cells Suppress HIV in Two PatientsThe Independent
world17 days agoDeveloping

Small Study Shows Modified Immune Cells Suppress HIV in Two Patients

Researchers reported that a single dose of genetically engineered CAR-T cells strongly suppressed HIV in two people for nearly one and two years without daily medication. The early-stage experiment modified immune cells to better target HIV-infected cells while protecting them fr…

The Independent
1 source
Study Reveals Role of Caspase-5 in Gut Tissue Repair and RegenerationGwénaël M. D. J.-M. Gaussand, Qi Jia, Eric van der Graaff, Gerda E. M. Lamers, Paul F. Fransz, Paul J. J. Hooykaas, Sylvia de Pater / Wikimedia (CC BY 3.0)
science31 days agoDeveloping

Study Reveals Role of Caspase-5 in Gut Tissue Repair and Regeneration

Researchers have identified an unusual function for the protein caspase-5 in promoting cell proliferation and tissue regeneration in the immature gut cells. The findings, published in Nature, suggest potential implications for understanding inflammatory bowel disease and colorect…

NA
1 source
Researchers Identify GPX4 Inhibitors That Target Senescent Cells in Cancer ModelsSubstrate placeholder — needs review
science35 days agoDeveloping

Researchers Identify GPX4 Inhibitors That Target Senescent Cells in Cancer Models

A study has identified GPX4 inhibitors that selectively kill senescent cells, which accumulate in tumors after chemotherapy. These compounds showed effectiveness in preclinical models of melanoma, prostate, and ovarian cancer. The findings suggest a potential new strategy for can…

ER
1 source
Study Finds Elevated Copper Levels in Regulatory T Cells of Rheumatoid Arthritis PatientsSubstrate placeholder — needs review
science40 days ago

Study Finds Elevated Copper Levels in Regulatory T Cells of Rheumatoid Arthritis Patients

A recent study has identified increased copper levels in regulatory T cells among patients with rheumatoid arthritis. This finding may inform the development of new treatments for autoimmune diseases. The research highlights potential therapeutic avenues based on these observatio…

SC
1 source
Study Identifies Long-Term T Cells in Nasal Tissue After Pathogen Infectionfuturity.org
science48 days ago

Study Identifies Long-Term T Cells in Nasal Tissue After Pathogen Infection

Researchers have found that nasal tissue contains T cells that retain memory of pathogens long after infection clears. The study, published in Nature, examined human nasal samples and mouse models to identify these resident memory T cells. This discovery provides insights into lo…

NA
1 source