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Eli Lilly's Mounjaro Becomes World's Top-Selling Drug in First Quarter

Mounjaro generated $8.7 billion in sales during the first quarter, surpassing Merck's Keytruda which recorded $7.9 billion. Keytruda had held the position of the world's best-selling drug since the beginning of 2023. The shift reflects changing revenue rankings among leading pharmaceutical products.

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indiatoday.intoday.in
2 sources·May 7, 4:45 PM(12 hrs ago)·1m read|
Eli Lilly's Mounjaro Becomes World's Top-Selling Drug in First Quarterindiatoday.intoday.in
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Eli Lilly's Mounjaro recorded $8.7 billion in sales in the first quarter, making it the world's best-selling drug. Merck's Keytruda, a cancer treatment, generated $7.9 billion in the same period. Keytruda had ranked as the top-selling drug since the start of 2023 before being overtaken by Mounjaro.

The company reported the first-quarter figures that placed Mounjaro ahead of all other pharmaceutical products worldwide.

Mounjaro's first-quarter performance exceeded Keytruda's by $800 million. The change ends a multi-year period during which Keytruda maintained the No. 1 position among all drugs by revenue. The updated rankings come from sales data for the three months ended March 31. No additional details on year-over-year growth rates or regional breakdowns were included in the report.

Key Facts

Mounjaro Q1 sales
$8.7 billion
Keytruda Q1 sales
$7.9 billion
Previous leader
Keytruda since start of 2023
New ranking
Mounjaro is world's top-selling drug
biotechdrug-saleseli-lillymerck

Story Timeline

3 events
  1. 2023

    Merck's Keytruda became the world's best-selling drug.

    1 source@MorningBrew
  2. 2026 Q1

    Mounjaro generated $8.7 billion while Keytruda generated $7.9 billion.

    1 source@MorningBrew
  3. 2026-05-08

    Sales data reported showing Mounjaro as the new top-selling drug.

    1 source@MorningBrew

Potential Impact

  1. 01

    Merck's Keytruda remains a leading cancer therapy with nearly $8 billion in quarterly sales.

  2. 02

    Eli Lilly's revenue from Mounjaro now exceeds that of Merck's former top product.

  3. 03

    The sales shift may influence investor perceptions of growth in diabetes and weight-loss treatments.

Transparency Panel

Sources cross-referenced2
Confidence score75%
Synthesized bySubstrate AI
Word count122 words
PublishedMay 7, 2026, 4:45 PM
Bias signals removed1 across 1 outlet
Signal Breakdown
Framing 1
Original Sources
@MorningBrewEli Lilly's Mounjaro is now the world's best-selling drug Q1 Sales: • Mounjaro............$8.7 bi...indiatoday.intoday.inMounjaro overtakes blockbuster cancer therapy Keytruda to become world's best-selling drugvia search

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